Jest autorem wielu książek i artykułów utrzymanych w polemicznym tonie poświęconych filozofii, sprawom społecznym i marksizmowi (najbardziej znaną dyskusję Lewis przeprowadził z Louisem Althusserem).

Prace Dzieła Lewisa The Old Testament in the 20th Century; A Faith to Live By; Christianity and the Social Revolution (red.); Textbook of Marxist Philosophy (red.); Douglas Fallacies: A Critique of Social Credit; The Philosophy of the Soviet State; An Introduction to Philosophy; The Case Against Pacifism; Marxism and Modern Idealism; The Basis of Soviet Philosophy; Marxism and the Open Mind; Religions of the World; Science, Faith, and Scepticism; Anthropology; Socialism and the Individual; A History of Philosophy; Man and Evolution; The Life and Teaching of Karl Marx; Bertrand Russell: Philosopher and Humanist; Naked Ape or Homo sapiens?; The Left Book Club: An Historical Record; The Marxism of Marx; Marxism and the Irrationalists; The Uniqueness of Man; Max Weber and Value Free Sociology: A Marxist Critique.