Przez Brent przebiegają cztery linie metra: Bakerloo Line, Jubilee Line, Metropolitan Line i Piccadilly line
Stacje metra: Alperton – Piccadilly line Dollis Hill – Jubilee Line Harlesden – Bakerloo Line Kensal Green – Bakerloo Line Kenton (na granicy z Harrow) – Bakerloo Line Kilburn – Jubilee Line Kilburn Parn – Bakerloo Line Kingsbury – Jubilee Line Neasden – Jubilee Line North Wembley – Bakerloo Line Northwick Park – Metropolitan Line Preston Road – Metropolitan Line Queensbury – Jubilee Line Queen’s Park – Bakerloo Line South Kenton – Bakerloo Line Stonebridge Park – Bakerloo Line Sudbury Hill (na granicy z Harrow) – Piccadilly line Sudbury Town – Piccadilly line Wembley Central – Bakerloo Line Wembley Park – Jubilee Line i Metropolitan Line Willesden Green – Jubilee Line Willesden Junction (na granicy z Hammersmith and Fulham) – Bakerloo Line
Pasażerskie połączenia kolejowe na terenie Brent obsługują przewoźnicy Chiltern Railways, Southern i London Overground.