125px|thumb|Ideogram over kromosom 3. Kromosom 3 er et af menneskets 23 kromosompar, og menneskets celler indeholder sædvanligvis to kopier af dette kromosom. Kromosom 3 omfatter mere end 198 millioner basepar http://vega.sanger.ac.uk/Homo_sapiens/mapview?chr=3 Kromosom 3 størrelse, Tilgået Januar 2018. (DNA's byggesten) og repræsenterer omkring 6.5% af det samlede DNA i cellerne.

Identificering af generne på hvert kromosom er et aktivt område inden for genforskningen. Eftersom forskerne benytter forskellige metoder til at anslå antallet af gener på hvert kromsom, findes der varierende angivelser af antallet. Kromosom 3 indeholder sandsynligvis i omegnen af 1.026 til 1.085 protein kodende gener.

Gener De følgende gener findes på kromosom 3:

p-arm De følgende er nogle af de gener der findes på p-armen (den korte arm) af det mennesklige kromosom 3: ALAS1: aminolevulinate, delta-, synthase 1 APEH: kodende enzym Acylamino-acid-releasing enzym ARPP-21: Cyclic AMP-regulerende phosphoprotein, 21 kDa AZI2: kodende protein 5-azacytidine-induced protein 2 BRK1: SCAR/WAVE actin nucleating complex subunit BRPF1: bromodomain og PHD finger containing 1 BTD: biotinidase C3orf60/NDUFAF3: kodende enzym NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 CACNA2D3: calcium channel, voltage-dependent, alpha 2/delta subunit 3 CCR5: chemokine (C-C motif) receptor 5 CGGBP1: CGG triplet repeat binding protein 1 CNTN4: Contactin 4 COL7A1: Collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant og recessive) DCLK3: Doublecortin like kinase 3 EAF1: ELL associated factor 1 ENTPD3: ectonucleoside triphosphate diphosphohydrolase 3 FBXL2: F-box og leucine rich repeat protein 2 FOXP1: Forkhead Box Protein P1 GMPPB: GDP-mannose pyrophosphorylase B HEMK1: kodende protein HemK methyltransferase family member 1 HIGD1A: HIG1 domain family member 1A LARS2: leucyl-tRNA synthetase, mitochondrial LIMD1: LIM domain-containing protein 1 MITF: microphthalmia-associated transcription factor MLH1: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) MYRIP: Myosin VIIA og Rab interacting protein NBEAL2: Neurobeachin-like 2 NKTR: NK-tumor recognition protein NPRL2: Nitrogen permease regulator 2-like protein OXTR: oxytocin receptor PTHR1: parathyroid hormone receptor 1 QRICH1: kodende protein QRICH1, also known as Glutamine-rich protein 1, RBM6: RNA-binding protein 6 RPP14: Ribonuclease P protein subunit p14 SCN5A: sodium channel, voltage-gated, type V, alpha (long QT syndrome 3) SETD5: SET domain containing 5 SFMBT1: Scm-like with four mbt domains 1 SLC25A20: solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 STT3B: catalytic subunit of the oligosaccharyltransferase complex SYNPR: synaptoporin TDGF1: Teratocarcinoma-derived growth factor 1 TMEM158: Transmembrane protein 158 TMIE: transmembrane inner ear TRAK1: trafficking kinesin-binding protein 1 TRANK1: kodende protein Tetratricopeptide repeat og ankyrin repeat containing 1 TUSC2: tumor suppressor candidate 2 UCN2: Urocortin-2 VGLL3: vestigial-like family member 3 VHL: von Hippel-Lindau tumor suppressor ZMYND10: zinc finger MYND-type containing 10 ZNF502: kodende protein Zinc finger protein 502 ZNF621: kodende protein Zinc finger protein 621

q-arm De følgende er nogle af de gener der findes på q-armen (den lange arm) af det mennesklige kromosom 3: ADIPOQ: adiponectin AMOTL2: kodende protein Angiomotin-like protein 2 ARHGAP31: Rho GRPase activating protein 31 CAMPD1: Camptodactyly CCDC80: Coiled-coil domain containing protein 80 CD200R1: Cell surface glycoprotein CD200 receptor 1 CLDND1: Claudin domain containing 1 CPN2: Carboxypeptidase N subunit 2 CPOX: coproporphyrinogen oxidase (coproporphyria, harderoporphyria) DPPA2: Developmental pluripotency associated 2 EAF2: ELL associated factor 2 EFCC1: EF-hand og coiled-coil domain containing 1 ETM1: Essential tremor 1 ETV5: ETS variant 5 FAM43A: family with sequence similarity 43 member A FAM162A: family with sequence similarity 162 member A GYG1: Glycogenin-1 HGD: homogentisate 1,2-dioxygenase (homogentisate oxidase) IFT122: intraflagellar transport gene 122 KIAA1257: KIAA1257 LMLN: kodende protein Leishmanolysin-like (metallopeptidase M8 family) LRRC15: leucine rich repeat containing 15 LSG1: large subunit GTPase 1 homolog MB21D2: kodende protein Mab-21 domain containing 2 MCCC1: methylcrotonoyl-Coenzym A carboxylase 1 (alpha) MYLK: Telokin NFKBIZ: NF-kappa-B inhibitor zeta PCCB: propionyl Coenzym A carboxylase, beta polypeptide PDCD10: programmeret cell død 10 PIK3CA: phosphoinositide-3-kinase, catalytic, alpha polypeptide PROSER1: Proline og serine rich protein 1 RAB7: RAB7, member RAS oncogene family RETNLB: resistin-like beta RHO: rhodopsin visual pigment RIOX2: Ribosomal oxygenase 2 SELT: Selenoprotein T SENP7: Sentrin-specific protease 7 SERP1: Stress-associated endoplasmic reticulum protein 1 SOX2: transcription factor SOX2OT: SOX2 overlapende transcript SRPRB: Signal recognition particle receptor subunit beta TM4SF1: Transmembrane 4 L6 family member 1 TRAT1: T-cell receptor-associated transmembrane adapter 1 USH3A: Usher syndrome 3A ZBED2: kodende protein Zinc finger BED-type containing 2 ZNF9: zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)

Relaterede sygdomme og uregelmæssigheder Nedenstående sygdomme har sammenhæng med varianter i gener, som hører til kromosom 3:

3-methylcrotonyl-CoA carboxylase deficiency 3q29 microdeletions syndrom Acute Myeloid Leukemi (AML) Alkaptonuria Arrhythmogenic right ventricular dysplasia Atransferrinemia Autisme Biotinidase deficiency Brugadas syndrom Carnitine-acylcarnitine translocase deficiency Cataracts Cerebral cavernous malformation Charcot-Marie-Tooth sygdom, type 2 Charcot-Marie-Tooth sygdom Chromosome 3q duplication syndrom Coproporphyria Dandy-Walker syndrom Døvhed Sukkersyge Dystrophic epidermolysis bullosa Essential tremors Grøn stær, primary open angle Glycogen storage sygdom Hailey-Hailey sygdom Hereditary coproporphyria Arvelig nonpolypøs tyk- og endetarmskræft HIV infection, susceptibility/resistance to Hypobetalipoproteinemia, familial Hypotermi Leukoencephalopathy with vanishing white matter Long QT syndrom Lymfeknudekræft Metaphyseal chondrodysplasia, Murk Jansen type Microcoria Moebius syndrom Moyamoya sygdom Mucopolysaccharidosis Myotonic dystrophy Night blindness Nonsyndromic deafness Ovarie kræft Porphyria Propionic acidemia Protein S deficiency Retinitis pigmentosa Romano-Ward syndrom Seckel Syndrom Sensenbrenner syndrom Septo-optic dysplasia Kort statur Spinocerebellar ataxia Sucrose intolerance Usher syndrom Von Hippel-Lindaus sygdom Waardenburg syndrom Xeroderma pigmentosum

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Kategori:Kromosomer Kategori:Homo sapiens