Tra i suoi brani più noti vi sono Duke of Earl (1961) e Groovy Situation (1969)
Discografia parziale 1962 - The Duke of Earl 1965 - Live on Stage in ‘65 1967 - The Girl Don't Care 1967 - The Duke of Soul 1968 - There Was a Time 1969 - The Two Sides of Gene Chandler 1970 - The Gene Chandler Situation 1971 - Gene and Jerry – One & One (con Jerry Butler) 1978 - Get Down 1979 - When You're Number One 1980 - '80 1981 - Here's to Love 1985 - Your Love Looks Good on Me 1995 - Tell It Like It Is
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