O cromossoma 15 é um dos 23 pares de cromossomas do cariótipo humano.
Genes Alguns genes localizados no cromossoma 15: CAPN3: Calpain 3 (limb-girdle muscular dystrophy type 2A) CHP: Calcium binding protein P22 FAH: fumarylacetoacetate hydrolase (fumarylacetoacetase) FBN1: fibrillin 1 (Marfan syndrome) HEXA: hexosaminidase A (alpha polypeptide)(Tay-Sachs disease) IVD: isovaleryl Coenzyme A dehydrogenase MCPH4: microcephaly, primary autosomal recessive 4 OCA2: oculocutaneous albinism II (pink-eye dilution homolog, mouse) RAD51: RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) STRC: stereocilin UBE3A: ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) PML: promyelocytic leukemia protein (involved in t(15,17) with RARalpha, predominant cause of acute promyelocytic leukemia. SLC24A5: the gene responsible for at least 1/3 of the skin color differences between races, expressed in the brain and the nervous system EYCL3 Eye color 3, BROWN - location: 15q11-q15 (note eye colour is a polygenic trait) EYCL2 Eye color 2,Determina o posicionamento dos melanócitos na íris (note eye colour is a polygenic trait) Doenças Síndrome de Prader-Willi Síndrome de Marfan Síndrome de Angelman Câncer de mama
Categoria:Genética humana